Main Ongoing
Projects
Zimmer ER et al. 2017, Nat Neurosci
Astrocytes in neurodegeneration
Astrocytes, a subtype of glial cells, are key players in controlling brain synapses and homeostasis. Recent evidence indicate they also contribute to the pathophysiology of neurodegenerative disorders. We are interested in understanding the specific role of these cells in neurodegeneration. To study astrocytes in health and disease our lab combines in vivo and in vitro techniques associated to computational and imaging data in mammals and humans.
Astrocytes in neurodegeneration
Astrocytes, a subtype of glial cells, are key players in controlling brain synapses and homeostasis. Recent evidence indicate they also contribute to the pathophysiology of neurodegenerative disorders. We are interested in understanding the specific role of these cells in neurodegeneration. To study astrocytes in health and disease our lab combines in vivo and in vitro techniques associated to computational and imaging data in mammals and humans.
Zimmer ER et al. 2017, Nat Neurosci
Brain networks in neurodegeneration
Brain imaging techniques are highly suited to understand how the brain works. It is thought that a high complex network that allows cells to communicate is needed for brain proper functioning. We are interested in evaluating brain changes in neurodegenerative disorders at the network level. For doing that, we build brain networks by deriving functional information from positron emission tomography (PET) imaging . We believe that these changes occur early in the neurodegenerative process, before the identification of pathological features or symptoms.
Bellaver B et al 2019, Brain Behav Immun
Brain networks in neurodegeneration
Brain imaging techniques are highly suited to understand how the brain works. It is thought that a high complex network that allows cells to communicate is needed for brain proper functioning. We are interested in evaluating brain changes in neurodegenerative disorders at the network level. For doing that, we build brain networks by deriving functional information from positron emission tomography (PET) imaging . We believe that these changes occur early in the neurodegenerative process, before the identification of pathological features or symptoms.
Zimmer ER., et al. 2017
Povala G, unpublished data